My research in image science is devoted to medical imaging, primarily emphasizing the development, assessment, and optimization of imaging systems for detecting cancer. One branch of the work is concerned with devising reliable models for predicting the diagnostic utility of new clinical imaging technology. The second and more expansive branch of work is directed at actually applying these predictive models to design and optimize diagnostic imaging systems. Current areas of interest include gamma-ray imaging with positron emission tomography (PET) and single-photon emission computed tomography (SPECT) and x-ray digital tomosynthesis (DT).

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