Plenary Presentation II
Presenter: Dr. Sorin Istrail, Brown University
Time: Saturday, February 4, 2006 (11:15 am - 12:15 pm)
Title: Harnessing Biological Complexity: From Genomics to Systems Biology
Abstract:
With the recent availability of tools for genome assembly, assembly comparison, and automatic annotation of genomes, genomics entered its post-genome sequence phase devoted to understanding the control systems of the cell. Building on its success in bio-molecular sequence analysis, comparative genomics is continually expanding its scope and methods by striving to better understand the components of the cell. In this talk, I will present an overview of our work in assembly comparison, protein folding, genetic variation, immunology, and genomic regulatory systems. The comparative genomics of the geometries of protein folds, patterns of inheritance of complex disease, immunopeptidomes, and logics of regulatory networks, provide pathways that will lead toward the acquisition of scientific control over major life processes.